tolbutamide

tolbutamide
tolbutamide [täl byo͞ot′ə mīd΄ ]
n.
[ TOL(U) + BUT(YRIC) + AMIDE]
an oral drug, C12H18N2O3S, that stimulates the pancreas to secrete more insulin, used to treat diabetes

English World dictionary. . 2014.

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  • Tolbutamide — Systematic (IUPAC) name N [(butylamino)carbonyl] 4 methylbenzenesulfonamide Clinical data AHFS/Drugs.com …   Wikipedia

  • tolbutamide — [ tɔlbytamid ] n. m. • v. 1960; de tol(yle), but(yle) et amide ♦ Méd. Sulfamide administré par voie buccale dans le traitement du diabète. ● tolbutamide ou tolglybutamide nom masculin Dénomination courante d un sulfamide hypoglycémiant …   Encyclopédie Universelle

  • tolbutamide — /tol byooh teuh muyd /, n. Pharm. a white crystalline substance, C12H18N2O3S, used to augment insulin secretion in the treatment of diabetes mellitus. [1955 60; TOL(U) + BUT(YL) + AMIDE] * * * ▪ drug       drug used in the treatment of type II… …   Universalium

  • tolbutamide sodium — the monosodium salt of tolbutamide, having the same actions as the base; used as a diagnostic test for insulinoma (tolbutamide test, q.v.) and for diabetes mellitus and other pancreatic disorders, administered intravenously …   Medical dictionary

  • tolbutamide test — (for insulinoma) one gram of tolbutamide is administered intravenously and plasma levels of glucose and insulin are monitored for 3 hours; prolonged hypoglycemia with hyperinsulinemia indicates presence of an insulinoma …   Medical dictionary

  • tolbutamide — noun Etymology: tol + butyric + amide Date: 1956 a sulfonylurea C12H18N2O3S used in the treatment of diabetes …   New Collegiate Dictionary

  • tolbutamide — A sulphonylurea that will bind to SUR and enhance insulin release from pancreatic B cells. Used in Type II diabetes (as are a number of similar drugs) …   Dictionary of molecular biology

  • tolbutamide — noun A drug that blocks potassium channels, used in the treatment of diabetes …   Wiktionary

  • tolbutamide — An orally active hypoglycemic agent used in the management of adult onset diabetes mellitus; it appears to stimulate the synthesis and release of endogenous insulin from functional islets; available as t. sodium for injection. * * *… …   Medical dictionary

  • tolbutamide — tol·bu·ta·mide …   English syllables

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